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NGB2904 HCl

CAS No. 189060-98-8

NGB2904 HCl ( NGB2904; NGB 2904; NGB-2904 )

产品货号. M23863 CAS No. 189060-98-8

NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥462 有现货
5MG ¥721 有现货
10MG ¥1126 有现货
25MG ¥2252 有现货
50MG ¥3969 有现货
100MG ¥5613 有现货
500MG ¥11745 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NGB2904 HCl
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively).
  • 产品描述
    NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
  • 同义词
    NGB2904; NGB 2904; NGB-2904
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT2;D1;D2;D3;D4;D5;α1 receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    189060-98-8
  • 分子量
    530.9
  • 分子式
    C28H30Cl3N3O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(c(cc1)cc(C2)c1-c1c2cccc1)NCCCCN(CC1)CCN1c1cccc(Cl)c1Cl.Cl
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. The dopamine D(3) receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017 Mar 18.
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